Radeon RX 6650M vs Quadro Plex 2200 S4

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Primary details

GPU architecture, market segment, value for money and other general parameters compared.

Place in the rankingnot rated112
Place by popularitynot in top-100not in top-100
ArchitectureTesla 2.0 (2007−2013)RDNA 2.0 (2020−2024)
GPU code nameGT200BNavi 23
Market segmentWorkstationLaptop
Release date25 July 2008 (16 years ago)4 January 2022 (2 years ago)

Detailed specifications

General parameters such as number of shaders, GPU core base clock and boost clock speeds, manufacturing process, texturing and calculation speed. Note that power consumption of some graphics cards can well exceed their nominal TDP, especially when overclocked.

Pipelines / CUDA cores2401792
Core clock speed648 MHz2068 MHz
Boost clock speedno data2416 MHz
Number of transistors1,400 million11,060 million
Manufacturing process technology55 nm7 nm
Power consumption (TDP)600 Watt120 Watt
Texture fill rate51.84270.6
Floating-point processing power0.6221 TFLOPS8.659 TFLOPS
ROPs3264
TMUs80112
Ray Tracing Coresno data28

Form factor & compatibility

Information on compatibility with other computer components. Useful when choosing a future computer configuration or upgrading an existing one. For desktop graphics cards it's interface and bus (motherboard compatibility), additional power connectors (power supply compatibility).

Laptop sizeno datalarge
InterfacePCIe 2.0 x16PCIe 4.0 x8
Length522 mmno data
Supplementary power connectorsno dataNone

VRAM capacity and type

Parameters of VRAM installed: its type, size, bus, clock and resulting bandwidth. Integrated GPUs have no dedicated video RAM and use a shared part of system RAM.

Memory typeGDDR3GDDR6
Maximum RAM amount4 GB8 GB
Memory bus width512 Bit128 Bit
Memory clock speed800 MHz2000 MHz
Memory bandwidth102.4 GB/s256.0 GB/s
Shared memory--

Connectivity and outputs

Types and number of video connectors present on the reviewed GPUs. As a rule, data in this section is precise only for desktop reference ones (so-called Founders Edition for NVIDIA chips). OEM manufacturers may change the number and type of output ports, while for notebook cards availability of certain video outputs ports depends on the laptop model rather than on the card itself.

Display ConnectorsNo outputsNo outputs

API compatibility

List of supported 3D and general-purpose computing APIs, including their specific versions.

DirectX11.1 (10_0)12 Ultimate (12_2)
Shader Model4.06.5
OpenGL3.34.6
OpenCL1.12.1
VulkanN/A1.3
CUDA1.3-

Pros & cons summary


Recency 25 July 2008 4 January 2022
Maximum RAM amount 4 GB 8 GB
Chip lithography 55 nm 7 nm
Power consumption (TDP) 600 Watt 120 Watt

RX 6650M has an age advantage of 13 years, a 100% higher maximum VRAM amount, a 685.7% more advanced lithography process, and 400% lower power consumption.

We couldn't decide between Quadro Plex 2200 S4 and Radeon RX 6650M. We've got no test results to judge.

Be aware that Quadro Plex 2200 S4 is a workstation card while Radeon RX 6650M is a notebook one.


Should you still have questions concerning choice between the reviewed GPUs, ask them in Comments section, and we shall answer.

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NVIDIA Quadro Plex 2200 S4
Quadro Plex 2200 S4
AMD Radeon RX 6650M
Radeon RX 6650M

Comparisons with similar GPUs

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Community ratings

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Questions & comments

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