RTX PRO 4000 Blackwell SFF vs Radeon Instinct MI250X

Primary details

GPU architecture, market segment, value for money and other general parameters compared.

Place in the rankingnot ratednot rated
Place by popularitynot in top-100not in top-100
ArchitectureCDNA 2.0 (2021)Blackwell 2.0 (2025)
GPU code nameAldebaranGB203
Market segmentWorkstationWorkstation
Release date8 November 2021 (3 years ago)11 August 2025 (recently)

Detailed specifications

General parameters such as number of shaders, GPU core base clock and boost clock speeds, manufacturing process, texturing and calculation speed. Note that power consumption of some graphics cards can well exceed their nominal TDP, especially when overclocked.

Pipelines / CUDA cores140808960
Core clock speed1000 MHz790 MHz
Boost clock speed1700 MHz1337 MHz
Number of transistors58,200 million45,600 million
Manufacturing process technology6 nm5 nm
Power consumption (TDP)500 Watt70 Watt
Texture fill rate1,496374.4
Floating-point processing power47.87 TFLOPS23.96 TFLOPS
ROPsno data96
TMUs880280
Tensor Coresno data280
Ray Tracing Coresno data70

Form factor & compatibility

Information on compatibility with other computer components. Useful when choosing a future computer configuration or upgrading an existing one. For desktop graphics cards it's interface and bus (motherboard compatibility), additional power connectors (power supply compatibility).

InterfacePCIe 4.0 x16PCIe 5.0 x8
Length267 mm167 mm
Width2-slot1-slot
Supplementary power connectors2x 8-pinNone

VRAM capacity and type

Parameters of VRAM installed: its type, size, bus, clock and resulting bandwidth. Integrated GPUs have no dedicated video RAM and use a shared part of system RAM.

Memory typeHBM2eGDDR7
Maximum RAM amount128 GB24 GB
Memory bus width8192 Bit192 Bit
Memory clock speed1600 MHz1125 MHz
Memory bandwidth3,277 GB/s432.0 GB/s
Resizable BAR++

Connectivity and outputs

This section shows the types and number of video connectors on each GPU. The data applies specifically to desktop reference models (for example, NVIDIA’s Founders Edition). OEM partners often modify both the number and types of ports. On notebook GPUs, video‐output options are determined by the laptop’s design rather than the graphics chip itself.

Display ConnectorsNo outputs4x mini-DisplayPort 2.1b

API and SDK compatibility

List of supported 3D and general-purpose computing APIs, including their specific versions.

DirectXN/A12 Ultimate (12_2)
Shader ModelN/A6.8
OpenGLN/A4.6
OpenCL3.03.0
VulkanN/A1.4
CUDA-12.0
DLSS-+

Pros & cons summary


Recency 8 November 2021 11 August 2025
Maximum RAM amount 128 GB 24 GB
Chip lithography 6 nm 5 nm
Power consumption (TDP) 500 Watt 70 Watt

Instinct MI250X has a 433.3% higher maximum VRAM amount.

RTX PRO 4000 Blackwell SFF, on the other hand, has an age advantage of 3 years, a 20% more advanced lithography process, and 614.3% lower power consumption.

We couldn't decide between Radeon Instinct MI250X and RTX PRO 4000 Blackwell SFF. We've got no test results to judge.

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AMD Radeon Instinct MI250X
Radeon Instinct MI250X
NVIDIA RTX PRO 4000 Blackwell SFF
RTX PRO 4000 Blackwell SFF

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