Radeon Instinct MI350X vs RX 6400

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Primary details

GPU architecture, market segment, value for money and other general parameters compared.

Place in the ranking336not rated
Place by popularitynot in top-100not in top-100
Cost-effectiveness evaluation40.11no data
Power efficiency27.18no data
ArchitectureRDNA 2.0 (2020−2025)CDNA 4.0 (2025−2026)
GPU code nameNavi 24MI350 256CU
Market segmentDesktopWorkstation
Release date19 January 2022 (4 years ago)12 June 2025 (1 year ago)
Launch price (MSRP)$159 no data

Cost-effectiveness evaluation

The higher the ratio, the better. We use the manufacturer's recommended prices.

no data

Performance to price scatter graph

Currently popular graphics cards are shown for comparison.

Detailed specifications

General parameters such as number of shaders, GPU core base clock and boost clock speeds, manufacturing process, texturing and calculation speed. Real power consumption of some graphics cards can well exceed their nominal TDP, especially if overclocked.

Pipelines / CUDA cores76816384
Core clock speed1923 MHz1000 MHz
Boost clock speed2321 MHz2200 MHz
Number of transistors5,400 million185,000 million
Manufacturing process technology6 nm3 nm
Power consumption (TDP)53 Watt1000 Watt
Texture fill rate111.42,252.8
Floating-point processing power3.565 TFLOPS72.09 TFLOPS
ROPs32no data
TMUs481024
Tensor Coresno data1024
Ray Tracing Cores12no data
L0 Cache192 KBno data
L1 Cache256 KB4 MB
L2 Cache1024 KB16 MB
L3 Cache16 MB256 MB

Form factor & compatibility

Information on compatibility with other computer components. Useful when choosing a future computer configuration or upgrading an existing one. For desktop graphics cards it's interface and bus (motherboard compatibility), additional power connectors (power supply compatibility).

InterfacePCIe 4.0 x4PCIe 5.0 x16
Lengthno data102 mm
Width1-slotOAM Module
Supplementary power connectorsNoneNone

VRAM capacity and type

Parameters of VRAM installed: its type, size, bus, clock and resulting bandwidth. Integrated GPUs have no dedicated video RAM and use a shared part of system RAM.

Memory typeGDDR6HBM3e
Maximum RAM amount4 GB288 GB
Memory bus width64 Bit8192 Bit
Memory clock speed2000 MHz2000 MHz
Memory bandwidth128.0 GB/s8.19 TB/s
Resizable BAR++

Connectivity and outputs

This section shows the types and number of video connectors on each GPU. The data applies specifically to desktop reference models (for example, NVIDIA’s Founders Edition). OEM partners often modify both the number and types of ports. On notebook GPUs, video‐output options are determined by the laptop’s design rather than the graphics chip itself.

Display Connectors1x HDMI 2.1, 1x DisplayPort 1.4aNo outputs
HDMI+-

API and SDK support

List of supported 3D and general-purpose computing APIs, including their specific versions.

DirectX12 Ultimate (12_2)N/A
Shader Model6.7N/A
OpenGL4.6N/A
OpenCL2.23.0
Vulkan1.3N/A
DLSS-+

Pros & cons summary


Recency 19 January 2022 12 June 2025
Maximum RAM amount 4 GB 288 GB
Chip lithography 6 nm 3 nm
Power consumption (TDP) 53 Watt 1000 Watt

RX 6400 has 1787% lower power consumption.

Instinct MI350X, on the other hand, has an age advantage of 3 years, a 7100% higher maximum VRAM amount, and a 100% more advanced lithography process.

We couldn't decide between Radeon RX 6400 and Radeon Instinct MI350X. We've got no test results to judge.

Be aware that Radeon RX 6400 is a desktop graphics card while Radeon Instinct MI350X is a workstation one.

Other comparisons

We selected several comparisons of graphics cards with performance close to those reviewed, providing you with more options to consider.

Community ratings

Here you can see the user ratings of the compared graphics cards, as well as rate them yourself.


4 2517 votes

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4.5 31 votes

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