EPYC 9456 vs 5 221E
Contents
Primary details
Comparing processor market type (desktop or notebook), architecture, sales start time and price.
| Place in the ranking | 485 | not rated |
| Place by popularity | not in top-100 | not in top-100 |
| Cost-effectiveness evaluation | 40.00 | no data |
| Market segment | Desktop processor | Server |
| Power efficiency | 11.35 | no data |
| Designer | Intel | AMD |
| Manufacturer | Intel | TSMC |
| Architecture codename | Bartlett Lake (2025−2026) | Venice (2004−2026) |
| Release date | 13 January 2025 (1 year ago) | 23 July 2026 (less than a year ago) |
| Launch price (MSRP) | $232 | $5,252 |
Cost-effectiveness evaluation
Performance per price, higher is better.
Performance to price scatter graph
Currently popular graphics cards are shown for comparison.
Detailed specifications
Basic parameters of Core 5 221E and EPYC 9456: number of cores, number of threads, base frequency and turbo boost clock, lithography, cache size and multiplier lock state. These parameters indirectly say of CPU speed, though for more precise assessment you have to consider their test results.
| Physical cores | 14 (Tetradeca-Core) | 48 (Octatetraconta-Core) |
| Threads | 20 | 96 |
| Base clock speed | 2.7 GHz | 3.2 GHz |
| Boost clock speed | 5.2 GHz | 3.7 GHz |
| L1 cache | 80 KB (per core) | 80 KB (per core) |
| L2 cache | 2 MB (per core) | 1 MB (per core) |
| L3 cache | 24 MB (shared) | 256 MB (shared) |
| Chip lithography | 10 nm | 2 nm |
| Die size | 257 mm2 | 4x 165 mm2 |
| Number of transistors | no data | 101,500 million |
| 64 bit support | + | + |
Compatibility
Information on Core 5 221E and EPYC 9456 compatibility with other computer components: motherboard (look for socket type), power supply unit (look for power consumption) etc. Useful when planning a future computer configuration or upgrading an existing one. Note that power consumption of some processors can well exceed their nominal TDP, even without overclocking. Some can even double their declared thermals given that the motherboard allows to tune the CPU power parameters.
| Number of CPUs in a configuration | 1 | 2 |
| Socket | 1700 | SP8 |
| Power consumption (TDP) | 65 Watt | 265 Watt |
Technologies and extensions
Technological solutions and additional instructions supported by Core 5 221E and EPYC 9456. You'll probably need this information if you require some particular technology.
| AES-NI | + | + |
| AVX | + | + |
| vPro | + | no data |
| Enhanced SpeedStep (EIST) | + | no data |
| Precision Boost 2 | no data | + |
Security technologies
Core 5 221E and EPYC 9456 technologies aimed at improving security, for example, by protecting against hacks.
| TXT | + | no data |
Virtualization technologies
Virtual machine speed-up technologies supported by Core 5 221E and EPYC 9456 are enumerated here.
| AMD-V | - | + |
| VT-d | + | no data |
| VT-x | + | no data |
Memory specs
Types, maximum amount and channel quantity of RAM supported by Core 5 221E and EPYC 9456. Depending on the motherboard, higher memory frequencies may be supported.
| Supported memory types | DDR4, DDR5 | DDR5 |
Graphics specifications
General parameters of integrated GPUs, if any.
| Integrated graphics card | Intel UHD Graphics 730 | N/A |
Peripherals
Specifications and connection of peripherals supported by Core 5 221E and EPYC 9456.
| PCIe version | 5.0 | 6.0 |
| PCI Express lanes | 20 | 128 |
Pros & cons summary
| Recency | 13 January 2025 | 23 July 2026 |
| Physical cores | 14 | 48 |
| Threads | 20 | 96 |
| Chip lithography | 10 nm | 2 nm |
| Power consumption (TDP) | 65 Watt | 265 Watt |
5 221E has 308% lower power consumption.
EPYC 9456, on the other hand, has an age advantage of 1 year, 243% more physical cores and 380% more threads, and a 400% more advanced lithography process.
We couldn't decide between Intel Core 5 221E and AMD EPYC 9456. We've got no test results to judge.
Note that Core 5 221E is a desktop processor while EPYC 9456 is a server/workstation one.
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